Cagrilintide is a long-acting amylin analog designed for research in appetite regulation and metabolic control. It mimics the activity of natural amylin, a hormone co-secreted with insulin, and is commonly studied for its effects on satiety, gastric emptying, and energy balance.
Intended Use:
Cagrilintide is intended for research purposes only. All peptides require reconstitution with bacteriostatic water (BAC water), sold separately.
Storage:
Store in a cool, dry place away from light. After reconstitution, keep refrigerated at 2–8°C.
Solubility:
Best reconstituted with bacteriostatic water. Gently swirl—do not shake.
Vial Size:
Typically supplied in lyophilized powder form (multi-dose vial, compatible with up to 3ml BAC water).
Shelf Life:
Lyophilized: up to 24 months when properly stored
Reconstituted: recommended use within 4–6 weeks
Handling:
Use sterile techniques during reconstitution and handling to maintain stability and integrity.
Cagrilintide works by mimicking a natural hormone called amylin, which is released alongside insulin after eating.
It helps regulate metabolism in three main ways:
Reduces appetite → sends signals to the brain to increase feelings of fullness
Slows gastric emptying → food stays in the stomach longer, reducing hunger spikes
Stabilizes energy intake → helps control how much and how often energy is consumed
Unlike GLP-1 alone, amylin pathways act through a different receptor system, which is why Cagrilintide is often studied in combination protocols for stronger appetite control effects.
Cagrilintide is a long‑acting acylated analogue of the pancreatic hormone amylin, designed for once‑weekly subcutaneous administration. It activates central amylin receptors to promote satiety, slow gastric emptying, and reduce food intake. In phase 2 and phase 3 trials, cagrilintide produced dose‑dependent weight loss with a predominantly gastrointestinal side‑effect profile.
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